Methamidophos, an Organophosphorus Insecticide, Induces Pro-aggressive Behaviour in Mice
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چکیده
منابع مشابه
Methylation of guanine in vivo by the organophosphorus insecticide methamidophos.
The methylating capability of methamidophos, assayed by the formation of [7-14C]methylguanine in mouse liver, was investigated using a 14C-insecticide labelled at the O--CH3 group. Following i.p. administration of the toxicant, [7-14C]methylguanine could be isolated from liver nucleic acids of treated mice. The amount of 14C-label reached its maximum 6 h following administration of the insectic...
متن کاملAcute organophosphorus insecticide poisoning in Sri Lanka.
Records of 92 cases of acute organophosphorus (OP) insecticide poisoning were analysed. Of the patients 91% were under 30 years of age and 86% were males. The common agents were Dimethoate, Methamidophos, Malathion, Monocrotophos and Fenthion. Poisoning was due to ingestion with suicidal intent in the majority. In addition to the acute cholinergic features, the other important manifestations we...
متن کاملPerinatal Exposure to Insecticide Methamidophos Suppressed Production of Proinflammatory Cytokines Responding to Virus Infection in Lung Tissues in Mice
Methamidophos, a representative organophosphate insecticide, is regulated because of its severe neurotoxicity, but it is suspected of contaminating agricultural foods in many countries due to illicit use. To reveal unknown effects of methamidophos on human health, we evaluated the developmental immunotoxicity of methamidophos using a respiratory syncytial virus (RSV) infection mouse model. Preg...
متن کاملPralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial
BACKGROUND Poisoning with organophosphorus (OP) insecticides is a major global public health problem, causing an estimated 200,000 deaths each year. Although the World Health Organization recommends use of pralidoxime, this antidote's effectiveness remains unclear. We aimed to determine whether the addition of pralidoxime chloride to atropine and supportive care offers benefit. METHODS AND FI...
متن کاملAggressive Behaviour
to more advanced techniques are provided at appropriate places throughout the text; and a comprehensive set of examples is provided at the end of each chapter. An intuitive rather than theoretical approach is stressed by the authors and thus some methods are presented almost entirely in "cook-book" style. With the exception of the material on analysis of frequencies presented in chapter 16, the...
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ژورنال
عنوان ژورنال: Neurotoxicity Research
سال: 2017
ISSN: 1029-8428,1476-3524
DOI: 10.1007/s12640-017-9750-9